Assay
Age
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Immunohistochemistry (section)
Postnatal
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Cryab crystallin, alpha B (Synonyms: alpha B-crystallin, Crya2, Crya-2, HspB5) | |
Results | Reference |
1* | J:63706 Brownell I, Dirksen M, Jamrich M, Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis. 2000 Jun;27(2):81-93 |
1 | J:139969 Cain S, Martinez G, Kokkinos MI, Turner K, Richardson RJ, Abud HE, Huelsken J, Robinson ML, de Iongh RU, Differential requirement for beta-catenin in epithelial and fiber cells during lens development. Dev Biol. 2008 Sep 15;321(2):420-33 |
1 | J:184297 Hu WF, Gong L, Cao Z, Ma H, Ji W, Deng M, Liu M, Hu XH, Chen P, Yan Q, Chen HG, Liu J, Sun S, Zhang L, Liu JP, Wawrousek E, Li DW, alphaA- and alphaB-crystallins interact with caspase-3 and Bax to guard mouse lens development. Curr Mol Med. 2012 Feb;12(2):177-87 |
1 | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1* | J:175263 Kenchegowda D, Swamynathan S, Gupta D, Wan H, Whitsett J, Swamynathan SK, Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Dev Biol. 2011 Aug 1;356(1):5-18 |
1 | J:242077 Mao M, Kiss M, Ou Y, Gould DB, Genetic dissection of anterior segment dysgenesis caused by a Col4a1 mutation in mouse. Dis Model Mech. 2017 Apr 01;10(4):475-485 |
1 | J:326946 Martin JB, Herman K, Houssin NS, Rich W, Reilly MA, Plageman TF Jr, Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts. Front Cell Dev Biol. 2022;10:840129 |
1 | J:95535 Min JN, Zhang Y, Moskophidis D, Mivechi NF, Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis. 2004 Dec;40(4):205-17 |
1 | J:305082 Pathak P, Blech-Hermoni Y, Subedi K, Mpamugo J, Obeng-Nyarko C, Ohman R, Molloy I, Kates M, Hale J, Stauffer S, Sharan SK, Mankodi A, Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCalpha and TSC2-mTOR downregulation. Commun Biol. 2021 Mar 19;4(1):355 |
1 | J:269956 Wada K, Matsushima Y, Tada T, Hasegawa S, Obara Y, Yoshizawa Y, Takahashi G, Hiai H, Shimanuki M, Suzuki S, Saitou J, Yamamoto N, Ichikawa M, Watanabe K, Kikkawa Y, Expression of truncated PITX3 in the developing lens leads to microphthalmia and aphakia in mice. PLoS One. 2014;9(10):e111432 |
1 | J:293760 Yu W, Yu Z, Wu D, Zhang J, Zhu Y, Zhang Y, Ning H, Wang M, Zhang J, Zhao J, Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway. Lab Invest. 2019 Nov;99(11):1714-1727 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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